PRODUCT DETAILS Pentablast Capsule is a gastrointestinal medicine, reduces the amount of acid your stomach makes. It is used to treat for indigestion, heartburn and acid reflux. Pentablast Capsule is also used for gastro-oesophageal reflux disease (GORD)-this is when you keep on getting acid reflux. Pentablast is also used to prevent and treat stomach ulcers.

GERD is a condition in which the valve (sphincter) located at the uppermost part of the stomach gets irritated and damaged due to excessive stomach acid production. As a result, stomach acid into the food pipe, leading to stomach upset and heartburn. Heartburn is the post effect of acid reflux with a burning-like feeling that rises from the stomach towards the neck.
Pentablast helps in reducing the stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall responsible for the release of gastric acid secretion - extra gastric acid secretion damage the tissues in the food pipe, stomach, and duodenum.

Uses of Pentablast Capsule:
Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, Peptic Ulcer

Medicinal Benefits
Pentablast Capsule helps in reducing the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger Ellison Syndrome in which the stomach makes an exceptionally high amount of acid.

Directions for Use
It is better to take Pentablast Capsule an hour before a meal. Pentablast Capsule should be swallowed whole with a glass of water. Do not crush, chew, or break it.

Storage
Store in a cool and dry place away from sunlight

Side Effects of Pentablast Capsule:
Like all medicines, Pentablast also has some common side effects. Pentablast Capsule might have some common side effects like headache, constipation, diarrhoea, and stomach pain. These side effects are temporary and may get resolve after some time. However, if side effects persists contact the doctor.
In-Depth Precautions and Warning

Drug Warnings
You should avoid taking Pentablast Capsule if you are allergic to H2 receptor blockers, have gastric cancer, liver disease, pregnant or planning for pregnancy, and breastfeeding mothers. Pentablast Capsule may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines. Intake of Pentablast Capsule may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous) immediately consult the doctor.

Drug Interactions
Drug-Drug Interaction: Pentablast interacts with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir) antacid (aluminium hydroxide). Let your doctor know if you are taking these medicines.
Drug-Food Interaction: Drinking alcohol and nicotine (tobacco) with Pentablast may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy.
Drug-Disease Interaction: Pentablast should be not given in patients with gastric bleeding, liver/ kidney disease, low vitamin B12 (anaemia).

Safety Advice
ALCOHOL
Drinking alcohol with Pentablast Capsule may cause dehydration and elevate the level of stomach acid, thereby decreasing its efficacy. So try to avoid consuming alcohol.

PREGNANCY
Please consult your doctor for advice before using Pentablast Capsule.

BREAST FEEDING
Please consult your doctor before intake of Pentablast Capsule. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

DRIVING
In some cases, Pentablast Capsule may cause dizziness, sleepy. If you observe these symptoms do not drive or operate machinery until you feel better.

LIVER
If you have or had a history or evidence of any liver-related diseases, please consult the doctor before taking medicine.

KIDNEY
If you have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking medicine.

Habit Forming
No

Diet & Lifestyle Advise
• Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
• Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
• Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents backflow of the stomach acid back into the food pipe.
• Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
• Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching