COMPOSITION
AMOXICILLIN 400MG & POTASSIUM CLAVULANATE 57 MG

MANUFACTURING/MARKETED BY
AVOGADRO LIFESCIENCES PVT LTD

PRICE-
MRP- RS 158

What is HARDCLAV DDS and how is it used?
HARDCLAV DDS is a prescription medicine used to treat the symptoms of many different infections caused by bacteria such as lower respiratory tract infections, chronic obstructive pulmonary disease, bacterial sinusitis, animal/human bite wounds, and skin infections. HARDCLAV DDS may be used alone or with other medications.

What are the possible side effects of HARDCLAV DDS?
HARDCLAV DDS may cause serious side effects including
• severe stomach pain,
• diarrhea which is watery or bloody,
• pale or yellowed skin,
• dark-colored urine,
• fever,
• confusion,
• weakness,
• loss of appetite,
• upper stomach pain,
• yellowing of skin or eyes (jaundice),
• easy bruising or bleeding,
• little or no urination,
• sore throat,
• swelling in your face or tongue,
• burning in your eyes,
• skin pain followed by a red or purple rash that spreads (on the face or upper body) with blisters and peeling

Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of HARDCLAV DDS include:
• nausea,
• diarrhea,
• vaginal itching or discharge,

Tell the doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of HARDCLAV DDS. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

DESCRIPTION
HARDCLAV DDS is an oral antibacterial combination consisting of amoxicillin and the beta-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid).

Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6 aminopenicillanic acid. The amoxicillin molecular formula is

C16H19N3O5S•3H2O, and the molecular weight is 419.46. Chemically, amoxicillin is (2S,5R,6R)-6-[(R)-(-)-2-Amino-2-(p-hydroxyphenyl)acetamido]-3,3- dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate and may be represented structurally as:


Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes. The clavulanate potassium molecular formula is C8H8KNO5, and the molecular weight is 237.25. Chemically, clavulanate potassium is potassium (Z)(2R,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]-heptane-2-carboxylate and may be represented structurally as:

PRECAUTION
• Read the label carefully before use
• Keep out of reach of the children
• Store in a cool dry place
• For 5+ years old males and females